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Which large language model for which clinical task

A task-first guide to choosing between language models, and what to check before you paste anything.

PDF · 10 pages · Updated 30 September 2026

Who it is for
Clinicians who use language models at work and want to choose by task, and to know what they may paste.
Format
PDF
Length
10 pages
Updated
30 September 2026
Topic
Comparisons

Three findings inside

  • 5%

    of 519 studies of health-care language models used real patient-care data.

    Systematic review, JAMA

  • 2 of 3

    leaders of the 2025 MedHELM paper no longer appear on its 14 May 2026 leaderboard.

    MedHELM leaderboard, 14 May 2026

  • 3 of 3

    evaluations were won by general-purpose models over two specialized clinical tools in one blinded benchmark.

    Blinded benchmark, Nature Medicine, 2026

What is inside

  1. How to use the guide
  2. A task-first decision tableLooking things up, drafting notes, summarising, messages, coding.
  3. Open-weight or closed: a trade-off, not a ranking
  4. Data handling: four patterns
  5. What a benchmark score does and does not show
  6. Before you paste anything

Get it

A task-first guide to choosing between language models, and what to check before you paste anything.

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Questions

Is this clinical or regulatory advice?

No. It appraises published evidence and sources. Confirm anything that affects a patient or a purchase with your own governance team and counsel.

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Which large language model for which clinical task

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